What is the best time of day to take it?

There is no right or ideal time, the most important thing is that you simply take them! If it's easy to do so during your morning routine, that's fine. Or before lunch. Or at night--it's all fine. They will do their job anytime they are consumed, because again, our bodies were designed to get SBO's on a regular basis, throughout the day before modern food processing became so prevalent.